Journal article

Is antenatal or early-life vitamin D associated with eczema or food allergy in childhood? A systematic review

Rong Zeng, Yusi Li, Songying Shen, Xiu Qiu, Chia-Lun Chang, Jennifer JJ Koplin, Kirsten PP Perrett, Shyamali CC Dharmage, Caroline JJ Lodge, Adrian JJ Lowe

Clinical and Experimental Allergy | Wiley | Published : 2023

Abstract

OBJECTIVE: To summarise the associations between antenatal or early-life blood vitamin D and the development of eczema/food allergy in childhood. DESIGN: A systematic review and meta-analyses were conducted to synthesize the published literature. Two reviewers independently performed the study selection and data extraction on Covidence. We assessed the risk of bias for observational studies by using the Newcastle-Ottawa Scale and the Cochrane Risk of Bias tool for clinical trials. The certainty of the evidence was assessed using Grading of Recommendations, Assessment, Development and Evaluations (GRADE). DATA SOURCES: We systematically searched PubMed and Embase from inception and April 20..

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Grants

Awarded by Centre of Research Excellence Food and Allergy Research


Awarded by Department of Science and Technology of Guangdong Province


Awarded by Guangzhou Municipal Science and Technology Bureau


Awarded by National Health and Medical Research Council


Awarded by National Natural Science Foundation of China


Funding Acknowledgements

Centre of Research Excellence Food and Allergy Research, Grant/Award Number: 1041420; Department of Science and Technology of Guangdong Province, Grant/Award Number: 2020B1111170001; Guangzhou Municipal Science and Technology Bureau, Grant/Award Number: 201807010086; National Health and Medical Research Council, Grant/Award Number: 1041420, 1145096, 1158699, 1193993, 2008019 and 2008911; National Natural Science Foundation of China, Grant/Award Number: 82173525